Veľmi často sa tu spomína selén napr. pri štítnej žľaze.
Ja som ho brala roky kvôli ortuti, aj štítnej žľaze a stále som nevedela, ktorá forma je pre mňa najoptimálnejšia, brala som síce tie chelátované, ale potom nejak logicky som sa zamerala len na selénové doplnky, kde sa získava selén priamo z potravy. A nedávno som natrafila na jeden zaujímavý článok, kde sa moje predpoklady potvrdili, lekár skúmal efektívnosť rôznych selénových doplnkov. Skúmal to tak, že svojim pacientom podával selén v rôznych formách a meral zvýšenie imunitných markerov, selén totiž priamo dokáže zvýšiť hodnotu bielych krviniek a je efektívny pri liečbe stafylokokových a plesňových infekcií, takisto niektoré formy neboli efektívne pri vylučovaní ortute
Takže ak beriete selén bežne kupovaný v obchodoch v chelátovanej forme, vôbec nemusí byť vo vašom organizme účinný, môže to mať dokonca negatívne vedľašie účinky!!!
Jednoznačne sa zamerajte na selén získavaný z potravy "food source" vo forme methylselenocysteine, 100% organické a telom využiteľné a to sú tieto:
http://www.iherb.com/Jarrow-Formulas-Se ... s/169?at=0http://www.iherb.com/Vibrant-Health-Gre ... Caps/14640http://www.healthdesigns.com/ecological ... 5-vegicapspríp. aj z kvasníc, vždy je to lepšia voľba ako hocijaká chelátovaná forma, jedine ak by ste mali problémy s kandidou:
http://www.iherb.com/Source-Naturals-Se ... blets/1379Takisto v tom článku píše ako niektoré firmy zavádzajú a klamú, napr. forma selenomethionine sa vyrába tak, že selén sa v laboratóriu pokúsi umelo naviazať na aminokyselinu methionin, ale niektoré firmy tento proces nemajú dobré zvládnutý a selén nie je plne zreagovaný s aminokyselinou, takže nakoniec zostane len anorganický selén a aminokyselina methionín:
http://www.keephopealive.org/j20031.html"L-Selenomethionine (made in a laboratory) is dropped from our list of recommended supplements.
Mark Konlee (July, 2002, monthly report) The issue of what kind of selenium compound is safe and effective, in helping to restore immune function, has been an open question for several years. In this issue, I believe we are making some real progress toward resolving this outstanding question. Since beginning this series of articles on selenium, in September of 2001, I have consistently recommended food sources of selenium, especially Brazil Nuts, along with selenium bound to either Methionine or Cysteine, and to avoid sodium selenite, because of toxicity issues.
With this month's report, we are no longer recommending L seleno-methionine (laboratory made) as a source of selenium, because of reported side effects and the absence of any noticeable benefits. Yes, we have changed our mind about this manufactured source of selenium. L-selenomethionine (SeM), as an amino acid chelate, is the most widely sold source of selenium available in health food stores, the other being sodium selenite. SeM is made in a laboratory under methods that try to bond selenium to the amino acid L-methionine.
Albion is a manufacturer of L-selenomethionine and other amino acid chelates, and wholesales its products to dietary supplement manufacturers. With daily usage of L-selenomethionine as high as 1800 mcg over a period of several weeks and months, there is no evidence that fungal and staph infections are decreasing, no evidence that white blood cell counts or CD4 counts are increasing, and no evidence of other tangible benefits, except for a few published studies that indicate a small decline in mercury levels for a dose as low as 100 mcg daily.
In contrast, the use of Brazil Nuts, the world's richest natural source of selenium, or supplements made from high selenium mustard greens (Ecological Formulas or Bio-Active Selenium by Solaray) or broccoli as in "Activated Selenium" by Jarrow Formulas, we are getting reports of increasing WBC and CD4 counts, the disappearance of fungal and staph infections, greater energy and well being, and in one case reported in this issue, an end to chronic fatigue syndrome. Most of these results are occurring very rapidly - often within the first week of use.
Ak sa použili para orechy, najbohatší zdroj selénu alebo doplnky vyrábané z horčičných rastlín príp. brokolice napr. od firmy Solaray a Jarrow, boli namerané zvýšené hodnoty WBC a CD4, zmizli plesňové a stafylokokové infekcie, zvýšená energia a pocit celkového zdravia, v jednom prípade zmizla chronická únava. Väčšina týchto výsledkov sa dostavila rýchlo - často v priebehu prvého týždňa užívania.
However, in five cases, where the Albion source of seleno-methionine was consumed in high daily doses, ranging from 1200 to 1600 mcg, there are no beneficial results to report. Two of the cases were CFIDS related and 3 HIV related, with two of the three HIV+ persons also using drug cocktails. Nothing in the lab results of any of these three cases indicates any increase in WBC counts, CD4 or CD8 counts, or even a decrease in the viral load. In all five cases, none of the participants used any other form of selenium, other than the synthetic L-selenomethionine that is made in a laboratory. Only one of the five persons using the Albion source of L-selenomethionine reported using foods rich in selenium, like Brazil nuts, ocean fish or seaweed nor did any of the five persons have blood serum levels of selenium tested after using the methionine bound selenium for several weeks.
Avšak v piatich prípadoch, kde bol konzumovaný selenomethion vo vysokých denných dávkach, od 1200 do 1600 mcg, neboli zaznamenané žiadne prospešné účinky. Dva z prípadov mali syndróm chronickej únavy, poruchy imunity a 3 HIV, v laboratórnych hodnotách neboli zaznamenané žiadne zmeny a zvýšenie WBC, CD4 alebo CD8 alebo dokonca zníženie virálnej záťaže. Adverse effects from high doses of "L-selenomethionine"
One reader with CFIDS took 1600 mcg daily of L-selenomethionine for several weeks and then had a numbing sensation on the right side of his body. He stopped using the selenium and fully recovered in a few days. After contacting me with this report, I initially was not convinced that the methionine bound selenium had anything to do with his symptoms, but suggested he switch to a food source of selenium and start with a low dose, 200 to 400 mcg daily, and gradually increase it. I also suggested he have his blood serum levels tested for selenium before starting on any new supplement. A second person using just 800 mcg daily of L selenomethionine noticed pain in the kidney area and stopped using it.
Note: Alternatives to L selenomethionine are high selenium yeast (Selenomax - available from Source Naturals), high selenium broccoli (Activated Selenium by Jarrow Formulas), high selenium mustard greens (Bio-Active Selenium by Solaray or Selenium Cruciferate by Ecological Formulas). Solaray also sells other forms of selenium, so read labels carefully to avoid buying the wrong stuff.
At this juncture, I am of the opinion that the Brazil nuts, high selenium mustard greens and broccoli, plus the high-selenium yeast, are the safest and most efficacious of all the selenium supplements. With high doses of selenomethionine, persons have also reported lung congestion, dermatitis and other skin conditions. Simon and Vale both reported adverse side effects from high doses of sodium selenite and selenomethionine. In an email from Simon in the UK, he said that at 1000 mcg daily of sodium selenite, his hair started falling out, but this stopped when he reduced the dose to 500 mcg daily. With equally high doses of selenomethionine, he reported big flare-ups of dermatitis. Both Vale and Simon reported the symptoms going away in a few days after stopping these selenium supplements. Another person, Del, also reported problems with high doses of selenomethionine. No one has reported any benefits.
All the reports of adverse effects are coming from the synthetic or laboratory made L-selenomethionine (amino acid chelates) and not from any known natural plant source of seleno methionine. The problem may be defects in the product, resulting from flaws in the manufacturing process.
Tento lekár nakoniec úplne prestal doporučovať svojim pacientom chelátované formy minerálov a zameral sa na iné formy, napr. citráty príp. najlepšie získavané z potravín.
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